[Acne inversa].
نویسندگان
چکیده
Acne inversa (synonyms are intertriginous acne, acne triad, acne tetrad, hidradenitis suppurativa, pyodermia fistulans sinifica) is a chronic inflammatory disorder of the sebaceous follicles and terminal hair follicles and is one member of the acne family. It is characterized by acne conglobata in an inverse pattern involving the axillary, inguinal, and perigenital regions, together with perifolliculitis and abscesses on the nape and scalp. The severity of the condition varies from a few suppurating lesions to widespread and disabling disease.
منابع مشابه
Acne Inversa: Evaluating Antimicrobial Peptides and Proteins
BACKGROUND Acne inversa is a chronic, suppurative relapsing inflammatory skin disease that primarily affects the axillae, perineum and inframammary regions. Evidence suggests that the innate immune system is involved in the pathogenesis of acne inversa. OBJECTIVE To investigate the role of the innate immune system in acne inversa. METHODS Skin biopsies were obtained from inflammatory skin l...
متن کاملAcne inversa.
Acne inversa is a chronic inflammatory skin disease featuring cutaneous and subcutaneous nodular inflammation, fistula formation and discharge of foul-smelling secretions. The disease can lead to functional impairment and psychological problems. There is inflammation of the terminal hair follicles in intertriginous regions, especially perianal, axillary and inguinal areas. Less often there is s...
متن کاملAcne inversa of the scrotum and penis – aggressive urological treatment
Acne inversa is a rare chronic and debilitating inflammatory skin disease. The authors report a case of a 45-year old male who presented with acne inversa in the inguinal, perineal, and scrotal areas. After unsatisfactory pharmacological treatment a wide surgical excision of the affected skin was performed in stages. On follow-up the patient presented with a very good cosmetic and functional re...
متن کاملToll-like receptor 2 is highly expressed in lesions of acne inversa and colocalizes with C-type lectin receptor.
BACKGROUND Acne inversa (hidradenitis suppurativa) is a chronic inflammatory and cicatricial disorder that affects skin areas rich in apocrine glands and terminal hairs, such as perineum and axillae. The exact pathogenesis of the disease is not well understood and the mechanisms by which bacterial superinfection contributes to the disease progression are not clear. Toll-like receptors (TLRs) ex...
متن کاملComorbidities of hidradenitis suppurativa (acne inversa).
Comorbidities of hidradenitis suppurativa (acne inversa) were reviewed by extracting original and review publications included in MEDLINE, EMBASE and COCHRANE libraries using the terms "hidradenitis," "Verneuil" and "acne inversa." Follicular occlusion disorders, inflammatory bowel diseases, especially Crohn disease, spondylarthropathy, other hyperergic diseases, genetic keratin disorders assoc...
متن کاملImprovement of Therapy Outcomes after Negative Pressure Wound Therapy in a Patient with Acne inversa
Treatment of acne inversa (also known as hidradenitis suppurativa) is complicated and chronic. This debilitating, inflammatory disease of the follicular sacks affects mostly young adults and has a strong negative impact on their quality of life. We present a case of a 28 year old woman with a history of acne inversa of Hurley grade 2 for 6 years. Patient underwent surgical excision of the skin ...
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ورودعنوان ژورنال:
- International journal of dermatology
دوره 37 2 شماره
صفحات -
تاریخ انتشار 1998